07 maart 2011

DNA machine

Using computer animation1 based on molecular research2 it is possible to see how DNA is actually copied in living cells. This animation shows the “assembly line” of biochemical machines which pull apart the DNA double helix and output a copy of each strand. The DNA to be copied enters the whirling blue molecular machine, called helicase, which spins it as fast as a jet engine as it unwinds the double helix into two strands. One strand is copied continuously, and can be seen spooling off on the other side. Things are not so simple for the other strand, because it must be copied backwards, so it is drawn out repeatedly in loops and copied one section at a time. The end result is two new DNA molecules.

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