“lower thalamic gating thresholds, resulting in decreased filtering and autoregulation of information flow and, increase excitation of cortical regions through decreased inhibition of prefrontal pyramidal neurons. The decreased prefrontal signal-to-noise ratio may place networks of cortical neurons in a more labile state, allowing them to more easily switch between representations and process multiple stimuli across a wider association range. This state, which we hereforth will refer to as the “creative bias”, could benefit performance on tasks that involve continuous generation and (re-)combination of mental representations and switching between mind-sets
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